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The Big Reveal on Wine vs. Breast Cancer


January 15, 2016 Blog » Wine News & Entertainment » The Big Reveal on Wine vs. Breast Cancer

Does wine increase the likeliness of breast cancer?! A recent study says yes, but did they jump the gun? Find out…

wine-vs-breast-cancer-wine-folly

Somewhere in Corning, New York, August 13, 2015

Me, Luiz and Lisa that night in Corning, NY.

It was a balmy late summer night in upstate New York at the wine blogger conference. I was there to promote the soon-to-be-released Wine Folly book at a large outdoor wine tasting. I ambled up to a longtime peer, Luiz Alberto who introduced me to Patrick Farrell, a Master of Wine. This is where things started to get weird. Patrick immediately jumped in about a recent study that showed how alcohol greatly increases the likeliness of breast cancer in women.

“Hold on… what?!”

Alberto looked at me gravely. I looked away and around the convention floor at the mostly female audience; glasses filled, laughing, chatting and carrying on… Was it true? Are we women putting ourselves in grave danger by drinking wine?

We all want to know the answer to this question.

After the convention I distracted myself and forgot the conversation until close to the holidays when it all came tumbling back. This time however, the reminder came in the form of an email from Dr. Edward Miller who is an advocate for intelligent wine drinking and he had some updated information about the study.

Below is our interview:
 

Talk to a Doc
First things first – everyone’s physiology is different. Talk to your doctor about your health before justifying health-altering behaviors based on the contents herein. Thank you!

Wine vs Breast Cancer: The Jury is Still Out

 

Wine Folly: Can you explain exactly what the study showed that has women so concerned?

Dr. Miller: Certainly. The study showed, namely, that women who drink light to moderate alcohol (1/2 to 1.5 drinks/day) showed a 1.6% overall increase in breast cancer risk. So, if the study is correct, women wine drinkers would see a raised lifetime risk of breast cancer from 12.4% to 14%.

 


You've got to be kidding me - doctor comic

Wine Folly: After the study came out it received some backlash/criticism from the scientific community. Can you explain to us what the issues were, how they affect us, and how they might affect the validity of the study?

 

Dr. Miller: There is valid criticism on several fronts.

First, the researchers ignored the overall impact of drinking. Study after study [(see references below)] has shown decreased overall death rates in light to moderate alcohol drinkers, primarily by decreasing cardiovascular deaths–the number one killer in the developed world. If women stop drinking altogether, many more will likely die of heart disease and diabetes than will potentially be saved by a few less cases of breast cancer. (1,2,3,4,5,6)

Secondly, a recent study showed a 34-46% decreased risk of death in women who are moderate to occasionally heavy alcohol users. (7)


 

“The unpublished data showed that women who drank 1-3 glasses of wine per day had no increased risk of breast cancer”

 


Thirdly, the study didn’t include cancers which are thought to be decreased by alcohol intake: kidney, thyroid, and non-Hodgkins lymphoma.

Fourth, they didn’t separate the type of alcohol drank – spirits, beer or wine. In addition, regular versus binge drinking wasn’t reported.

Most significantly to your readers, analysis of the supplemental data not included in the original study revealed different findings which could have lead to a different conclusion. The unpublished data showed that women who drank 1-3 glasses of wine per day had no increased risk of breast cancer while liquor and beer drinkers experienced a 26 and 34% increase, respectively. (8)

alcohol-use-cancer-heart-wine-beer
The Annals of Internal Medicine (2000)

Wine Folly: To support this argument you forwarded along some charts from another study (above). What can we learn by observing this data?
 

Dr. Miller: The Annals of Internal Medicine published a study which showed decreased cancer deaths in wine drinkers but not in beer or spirits drinkers. To my knowledge, no medical study has shown increased cancer deaths in wine drinkers. That must be somewhat tempered by the fact that wine drinkers, on average, are a little different than consumers of other alcohol beverages: they are thinner, eat more grains and exercise more – all of which reduce cancer risk. (9)

Several other studies have shown about a 20% overall reduced risk of cancers with wine consumption which is not seen with beer or spirit consumption. (10, 11, 12, 13)


Should I get my boobs chopped off?
Wine Folly: Finally, I’ve heard that folic acid is an important substance to reduce the risk of breast cancer. But I’ve also heard that drinking a glass or two of wine a day will decrease folic acid uptake? Can you tell us more about this relationship?

 

Dr. Miller: Many studies have looked for a link between what women eat and breast cancer risk, but so far the results have been conflicting. Some studies have indicated that diet may play a role, while others found no evidence that diet influences breast cancer risk. Studies have also looked at vitamin levels, again with inconsistent results. Some studies actually found an increased risk of breast cancer in women with higher levels of certain nutrients. So far, no study has shown that taking vitamins reduces breast cancer risk. This is not to say that there is no point in eating a healthy diet. A diet low in fat, low in red meat and processed meat, and high in fruits and vegetables might have other health benefits.

While many organizations are actively studying folic acid and multivitamin supplementation (including Susan G. Komen), preliminary evidence suggests that high doses of folic acid (also known as folate) may actually increase the risk of breast cancer. Having said that, folic acid is an essential “B” vitamin which the body requires. Excessive alcohol intake has been shown to decrease absorption of folate.


Wine Folly: Have any last thoughts for us about what we may do that could continue to decrease the risk of breast cancer? (e.g. should I be taking my vitamins? should I drink smarter?).
 

Dr. Miller: Risk factors for breast cancer include: advancing age, mothers or sisters with breast cancer, smoking and physical inactivity. You can’t help your age or choose your parents but you can be physically active, not smoke and drink alcohol sensibly. While alcohol does appear to mildly increase the risk of breast cancer, wine may not affect risk or may even decrease the risk. Talk to your health care provider about your breast cancer risk and appropriate screening. There are so many things out there that may be bad for you… you can live your life under your bed in fear or you can enjoy life.


 

“you can live your life under your bed in fear or you can enjoy life.”

 


 

About Dr. Edward Miller

Dr. Miller is an advanced-level certified wine sommelier from the International Wine & Spirits Guild. He administers a Facebook page, “Don’t Drink Too Much but Don’t Drink Too Little” which regularly addresses the role of wine & alcohol in health. He and his wife are physicians in St. Thomas, US Virgin Islands.

 

Sources

  1. Di Castelnuovo A, Rotondo S, Iacoviello L, Donati MB, de Gaetano G. Meta-analysis of wine and beer consumption in relation to vascular risk. Circulation 2002;105:2836–44.
  2. Corrao G, Bagnardi V, Zambon A, La Vecchia C. A meta-analysis of alcohol consumption and the risk of 15 diseases. Prev Med 2004;38: 613–9.
  3. Reynolds K, Lewis B, Nolen JD, Kinney GL, Sathya B, He J. Alcohol consumption and risk of stroke: a meta-analysis. JAMA 2003;289: 579–88.
  4. Corrao G, Rubbiati L, Bagnardi V, Zambon A, Poikolainen K. Alcohol and coronary heart disease: a meta-analysis. Addiction 2000; 95:1505–23.
  5. Rimm EB, Klatsky A, Grobbee D, Stampfer MJ. Review of moderate alcohol consumption and reduced risk of coronary heart disease: is the effect due to beer, wine, or spirits? BMJ 1996;312:731–6.
  6. Klatsky AL. Alcohol, cardiovascular diseases and diabetes mellitus. Pharmacol Res 2007;55:237–47.
  7. Am J Epidemiol 2011;173:319-29
  8. Critique of Update on the Association of Alcohol Consumption with Risk of Cancer
  9. Ref: Ann Int Med 133:411-19, 2000
  10. Arch Int Med 159:1865, 1999
  11. Br Med J 310:1165, 1995
  12. Circulation 105:2836, 2002
  13. J Am Coll Cardiol: 41:151, 2003


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By Madeline Puckette
I'm a certified wine geek with a passion for meeting people, travel, and delicious food. You often find me crawling around dank cellars or frolicking through vineyards. Find me at @WineFolly